CiVentiAnalytical offers advanced chromatographic method development using cutting edge design of experiment statistical software and utilizing a quality by design approach. Traditional trial and error based method development is very time consuming and relies on a linear progression based on what the analyst thinks mite work and often at best yields a useable method after much experimentation.

Our quality by design approach allows us to screen a wide variety of conditions, analyze multiple variables at once and build a statistical model of the separation that help us to optimize a method while avoiding dead ends.

By coupling this with an automated column and solvent switching valve CiVentiAnalytical quickly sets up screening experiments overnight or even over an entire weekend. By collecting a large amount of data we can determine the best column, the best mobile phase and understand exactly how each parameter governs the separation. With this knowledge we can set up further screening experiment to optimize the method based on your specific goals for the method, including peak resolution, run time and even utilize the screening data to do robustness prediction calculations before validation.

What this means for our clients is that you will get the BEST method in less time..